Friday, 16 May 2014
Antibiotic AuPt nanoparticles
Researchers have discovered that bimetallic nanoparticles containing gold and platinum act as antimicrobial agents and are effective against a range of bacteria including E.coli, Salmonella Choleraesius and Pseudomonas Aeruginosa. Pure gold or pure platinum nanoparticles were not antibiotic at all. Investigations suggested two mechanisms in operation: disruption of the cell membranes and increased intracellular ATP. The nanoparticles were not toxic to mammalian cells in vitro.
Tuning the Composition of AuPt Bimetallic Nanoparticles for Antibacterial Applications, Y. Zhao et al, Angewandte Chemie International Edition, DOI: 10.1002/anie.201401035