Wednesday, 7 May 2014
Non-invasive monitoring of fetal development
Researchers probed the temporal dynamics of gene transcription in the cell-free RNA of pregnant women’s blood plasma. Microarray techniques and next-generation sequencing data identified and quantified transcripts from specific fetal tissues and placenta. Findings suggest a route to diagnosing pregnancy complications and fetal abnormalities. Methods might also identify neurodegenerative disorders.
Noninvasive in vivo monitoring of tissue-specific global gene expression in humans; W. Koh et al; PNAS; doi: 10.1073/pnas.1405528111