A run of protein-based materials papers (excluding
yesterday’s dialysis paper). Apologies
for this – I do try to be diverse in content.
But this one is from my own journal Nature so I couldn’t
resist. Here it is.
Researchers have described the precise self-assembly
of protein nanomaterials from two novel co-assembling protein subunits. Computational methods were used to predict amino
acid sequences (one for each subunit) which would stabilize the interfaces
between the folded subunits and drive assembly of multiple copies into a specific
symmetric architecture. The researchers
experimentally verified the computational methods by fabricating five different
two-component co-asssembled nanomaterials each forming one of two targeted
tetrahedral architectures.
Accurate
design of co-assembling multi-component protein nanomaterials; N.P. King et al; Nature AOP;
doi:10.1038/nature13404
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